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Paul Wolujewicz

Paul Wolujewicz

Assistant Professor of Medical Sciences

Welcomes Media Inquiries
Paul Wolujewicz

Assistant Professor of Medical Sciences

Welcomes Media Inquiries
Dr. Paul Wolujewicz is an Assistant Professor of Medical Sciences at the Frank H. Netter MD School of Medicine at Quinnipiac University, with a joint appointment as Assistant Professor of Biomedical Sciences in the School of Health Sciences. He earned his BS in Biophysics, MS in Biomedical Sciences, MPH in Biostatistics and Epidemiology, and PhD in Physiology, Biophysics, and Systems Biology. He completed his postdoctoral training at Weill Cornell Medicine, where he serves as an Adjunct Assistant Professor of Neuroscience in the Brain & Mind Research Institute. He is also a Research Affiliate at the Connecticut Agricultural Experiment Station, where he collaborates on genomic and epidemiological surveillance of vector-borne diseases.

At the Netter School of Medicine, Dr. Wolujewicz teaches in the pre-clerkship curriculum with a focus on neuroscience and neurology, and mentors medical students on research and capstone projects. He teaches Computational Biomedicine and co-teaches Machine Learning in Medical Sciences, graduate courses cross-listed between the School of Medicine and the School of Health Sciences. He also teaches Biomedical Genomics and Cellular Basis of Neurobiological Disorders within the School of Health Sciences. Across both schools, he is committed to training students in modern experimental and computational methods for careers in medicine, biomedical research, and data science.

The Wolujewicz Lab combines hands-on genomics with computational and machine learning approaches to investigate the genetic architecture of neurological and neurodevelopmental disorders, including neural tube defects. The lab integrates whole-genome sequencing and multi-omic analyses with experimental validation through collaborations across Quinnipiac and Weill Cornell. Dr. Wolujewicz works with pediatric clinical partners in Connecticut to establish a family-based spina bifida biorepository, creating a foundation for research into the genetic and environmental risk factors that contribute to spina bifida. The lab also uses in-house nanopore sequencing to perform metagenomic analysis of field-collected ticks, detecting and characterizing vector-borne pathogens for public health surveillance.

Education

  • MS, Rutgers-The State Univ of NJ
  • MPH, Rutgers-The State Univ of NJ
  • PHD, Cornell University-Ny
  • PHD, Cornell University

Areas of Expertise

  • Biomedical Genomics
  • Biotechnology
  • Population Health
  • Neurology/Neuroscience
  • Computational Biomedicine

Organization

  • Medicine

Mail Drop

  • NH-MED

Courses

Quinnipiac Today

Experience

Quinnipiac University

Assistant Professor of Medical Sciences

North Haven, CT

2026 - Present

Quinnipiac University

Assistant Professor of Biomedical Sciences

Hamden, CT

2023 - Present

Weill Cornell Medical College

Adjunct Assistant Professor of Neuroscience

New York, NY

2023 - Present

Weill Cornell Medical College

Postdoctoral Associate in Neuroscience

New York, NY

2022 - 2023

Selected Publications

Peer Reviewed Presentations

Evidence for Pathogenic Expansions in NTD Case-Parent Trios

Paul Wolujewicz, Vanessa Aguiar-Pulido, Megan Shuguli, Sarah Fazal, Gregory Heuer, Osvaldo M. Mutchinick, Jose Suazo, Pablo Alacron, Adolfo Aguayo Gómez, Richard H. Finnell, Rosa A. Pardo, M. Elizabeth Ross

International Conference on Neural Tube Defects, Vancouver, Canada, University of British Columbia (2024)

Peer Reviewed Journal

Schizophrenia endothelial cells exhibit higher permeability and altered angiogenesis patterns in patient-derived organoids

Isidora Stankovic, Michael Notaras, Paul Wolujewicz, Tyler Lu, Raphael Lis, Margaret Elizabeth Ross, Dilek Colak

Translational Psychiatry (2024)

Peer Reviewed Journal

Integrative computational analyses implicate regulatory genomic elements contributing to spina bifida.

Wolujewicz P, Aguiar-Pulido V, Thareja G, Suhre K, Elemento O, Finnell RH, Ross ME.

Genetics in Medicine Open (2024)

Peer Reviewed Journal

A non-coding insertional mutation of Grhl2 causes gene over-expression and multiple structural anomalies including cleft palate, spina bifida and encephalocele.

Crane-Smith, Z., De Castro, S. C. P., Nikolopoulou, E., Wolujewicz, P., Smedley, D., Lei, Y., Mather, E., Santos, C., Hopkinson, M., Pitsillides, A. A., Genomics England Research Consortium, Finnell, R. H., Ross, M. E., Copp, A. J., & Greene, N. D. E.

32(17) Human molecular genetics 2681–2692 (2023)

Peer Reviewed Journal

Astrocytes derived from ASD individuals alter behavior and destabilize neuronal activity through aberrant Ca2+ signaling.

Allen, M., Huang, B. S., Notaras, M. J., Lodhi, A., Barrio-Alonso, E., Lituma, P. J., Wolujewicz, P., Witztum, J., Longo, F., Chen, M., Greening, D. W., Klann, E., Ross, M. E., Liston, C., & Colak, D.

Molecular psychiatry (2022)

Peer Reviewed Journal

Systems biology analysis of human genomes points to key pathways conferring spina bifida risk.

Aguiar-Pulido, V., Wolujewicz, P., Martinez-Fundichely, A., Elhaik, E., Thareja, G., Abdel Aleem, A., Chalhoub, N., Cuykendall, T., Al-Zamer, J., Lei, Y., El-Bashir, H., Musser, J. M., Al-Kaabi, A., Shaw, G. M., Khurana, E., Suhre, K., Mason, C. E., Elemento, O., Finnell, R. H., & Ross, M. E.

Proceedings of the National Academy of Sciences (2021)

Peer Reviewed Journal

Genome-wide investigation identifies a rare copy-number variant burden associated with human spina bifida.

Wolujewicz P, Aguiar-Pulido V, AbdelAleem A, Nair V, Thareja G, Suhre K, Shaw GM, Finnell RH, Elemento O, Ross ME.

Genetics in Medicine (2021)

Peer Reviewed Journal Article Review

Unraveling the complex genetics of neural tube defects: From biological models to human genomics and back.

Wolujewicz P, Steele JW, Kaltschmidt JA, Finnell RH, Ross ME.

Genesis (2021)