Dennis Addy ’25, Abigail Lambert, MS ’26, and Steven Ramirez Espinal, MS ’26, worked alongside Sanoji Samarakkody, assistant professor of biomedical sciences, to develop innovation and groundbreaking biological research.

This work was made possible thanks to a grant provided by the School of Health Sciences and Department of Biomedical Sciences.

Their research focused on the broad field of DNA damage and its predisposition to cancer. The students investigated the DNA damage response pathways using small molecule inhibitors on human breast cancer cells. Their research results show that using these mole inhibitors can reduce modulate the DNA damage response and potentially be used to treat or mitigate the risk of certain cancers.

Prior to this research, the students were prepared for this work through their coursework at Quinnipiac.

“My lab and class activities were fundamental in making this study a success. I had the opportunity to ask questions and get answers about anything confusing in a course,” said Addy.

The other students agreed the support from Samarakkody prepared them for this research and future work.

“Throughout the course, I participated in activities that emphasized public speaking and effectively communicating our research. Also, Dr. Samarakkody provided close mentorship and guidance throughout the process. This combination helped us refine our presentation and confidently present our research in a clear and engaging way at the conference,” said Lambert.

“Quinnipiac provided access to a structured research environment that enabled me to design experiments, troubleshoot methods, and develop independence as a researcher while also mentoring others. I am very grateful for the opportunity that Quinnipiac has provided me to conduct research and enhance my skills,” said Ramirez Espinal. “Conducting this project enhanced my ability to think critically, analyze data and approach medical problems from a mechanistic perspective.”

The students shared their research at the CellBio25 conference through a poster presentation and learned from peers and colleagues from across the world.

"At the conference, I observed a wide range of research presentations and gained insight into how other scientists approach similar questions. I also identified potential improvements and future applications for our own research. Being surrounded by fellow scientists for several days empowered me to continue to grow,” said Lambert.

“The conference provided valuable opportunities for networking, feedback and professional growth. The greatest benefit for me was learning from others, seeing thousands of scientists share their knowledge, each working in different areas yet united by a common goal, to understand the world better through science," said Ramirez Espinal.